Anavar is no doubt the safest one to use. In fact, this drug is commonly used in children for treatment of various diseases. There is even little use of ancillary medicaments when taking Anavar. This steroid doesn’t aromatize, and estrogenic side-effects are virtually non-existent. Androgenic side-effects of oxandrolone are so mild, that it is commonly used to treat medical conditions in women. This is why Anavar is very popular with women athletes. Most importantly, Anavar has very limited effects on HPTA (hypothalamic-pituitary-gonadal axis) meaning it will not stop your natural testosterone production unless used for very long period.